4pgz/2/1:B/1:A

Sequences
>4pgz-a2-m1-cB (length=193) [Search sequence]
DKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENE
SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILIRLVNLQCVAAG
FPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECK
AYNDVGKTSAYFN
>4pgz-a2-m1-cA (length=197) [Search sequence]
VDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSEN
ESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILIRLVNGMLQCV
AAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTV
ECKAYNDVGKTSAYFNF
Structure information
PDB ID 4pgz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structural basis of KIT activation by oncogenic mutations in the extracellular region reveals a zipper-like mechanism for ligand-dependent or oncogenic receptor tyrosine kinase activation
Assembly ID 2
Resolution 2.4Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 67
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession P10721 P10721
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4pgz-a2-m1-cB_4pgz-a2-m1-cA.pdb.gz
Full biological assembly
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Download: 4pgz-assembly2.cif.gz

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