4pl4/1/1:B/1:A

Sequences

>4pl4-a1-m1-cB (length=384) [Search sequence]

RMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDE HPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHS LNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLVPGTEGWIAPEMLSPTYTVDIFS AGCVFYYVISEGYHPFGKSLQRQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQQ RPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENIT VPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPH LLSHTYQAMELCRHERLFQTYYWH

>4pl4-a1-m1-cA (length=385) [Search sequence]

RMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDE HPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHS LNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVPGTEGWIAPEMLSPTYTVDIF SAGCVFYYVISEGYHPFGKSLQRQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQ QRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENI TVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFP HLLSHTYQAMELCRHERLFQTYYWH

Structure information

PDB ID	4pl4 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of murine IRE1 in complex with OICR464 inhibitor
Assembly ID	1
Resolution	3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	29
Sequence identity between the two chains	1.0
PubMed citation	25164867

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	Q9EQY0	Q9EQY0
Species	10090 (Mus musculus)	10090 (Mus musculus)
Function annotation	BioLiP:4pl4B	BioLiP:4pl4A

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 4pl4-a1-m1-cB_4pl4-a1-m1-cA.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 4pl4-assembly1.cif.gz

Similar dimers