4pw8/2/1:E/1:H

Sequences
>4pw8-a2-m1-cE (length=293) [Search sequence]
IYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNG
HVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRL
LENKIGVLQEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEE
FIRQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQ
LLTSLMDIDSLMTKWRYNHVCMVHRMLGSYKVFVDLFNLSTYLIPRHWIPKMN
>4pw8-a2-m1-cH (length=301) [Search sequence]
LIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQN
GHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFR
LLENKIGVLQEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEE
EFIRIQAKEEEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYRE
EPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLRYKVFVDLFNLSTYLIPRHWIPKM
N
Structure information
PDB ID 4pw8 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Human tryptophan 2,3-dioxygenase
Assembly ID 2
Resolution 2.902Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 14
Sequence identity between the two chains 0.993
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID E H
UniProt accession P48775 P48775
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4pw8-a2-m1-cE_4pw8-a2-m1-cH.pdb.gz
Full biological assembly
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Download: 4pw8-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 4pw8/2/1:E/1:G 4pw8/1/1:A/1:C
  • 4pw8/2/1:E/1:F 4pw8/1/1:B/1:A 6a4i/1/1:B/1:A
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