4q50/5/1:H/2:E

Sequences

>4q50-a5-m1-cH (length=218) [Search sequence]

ALSLTADQMVSALLDAEPPILYSEYASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHD
QVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSR
FRMMNLQGEEFVCLKSIILLNSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQ
HQRLAQLLLILSHIRHMSNKGMEHLYPLYGLLLEMLDA

>4q50-a5-m2-cE (length=218) [Search sequence]

LALSLTADQMVSALLDAEPPILYSEYASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH
DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVGMVEIFDMLLATSSR
FRMMNLQGEEFVCLKSIILLNSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQ
HQRLAQLLLILSHIRHMSNKGMEHLYSMLYGLLLEMLD

Structure information

PDB ID	4q50 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen
Assembly ID	5
Resolution	3.07Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	41
Sequence identity between the two chains	0.986
PubMed citation	26836308

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	H	E
UniProt accession	P03372	P03372
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4q50H	BioLiP:4q50E

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

4q50-a5-m1-cH_4q50-a5-m2-cE.pdb.gz

Full biological assembly

Download:

4q50-assembly5.cif.gz