4q50/5/2:B/2:C

Sequences
>4q50-a5-m2-cB (length=209) [Search sequence]
ALSLTADQMVSALLDAEPPILYSEMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVH
LLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCGMVEIFDMLLATSSRFRMMN
LQGEEFVCLKSIILLNSGVLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMLYGLLLEMLD
>4q50-a5-m2-cC (length=220) [Search sequence]
LALSLTADQMVSALLDAEPPILYSESMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQ
VHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVMVEIFDMLLATSSRFRM
MNLQGEEFVCLKSIILLNSGVYTSSTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQH
QRLAQLLLILSHIRHMSNKGMEHLYSVVPLYGLLLEMLDA
Structure information
PDB ID 4q50 (database links: RCSB PDB PDBe PDBj PDBsum)
Title The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen
Assembly ID 5
Resolution 3.07Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 40
Sequence identity between the two chains 0.99
PubMed citation 26836308
Chain information
Chain 1 Chain 2
Model ID 2 2
Chain ID B C
UniProt accession P03372 P03372
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4q50B BioLiP:4q50C
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 4q50-a5-m2-cB_4q50-a5-m2-cC.pdb.gz
Full biological assembly
Download: 4q50-assembly5.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 4q50/5/2:B/2:E 4q50/1/1:A/1:F 4q50/2/1:B/1:E 4q50/5/1:A/1:F 7sfo/1/1:A/1:B
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