4rlo/3/1:B/1:A

Sequences

>4rlo-a3-m1-cB (length=254) [Search sequence]

KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKKHPFIVDLIYAFQTGGK LYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLN HQGHVKLTDFGLCKESITIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENR KKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWE ELLARKVEPPFKPL

>4rlo-a3-m1-cA (length=259) [Search sequence]

KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAERNILEEVKHPFIVDL IYAFQTKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLK PENIMLNHQGHVKLTDFGLCKEGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPP FTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF RHINWEELLARKVEPPFKP

Structure information

PDB ID	4rlo (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Human p70s6k1 with ruthenium-based inhibitor EM5
Assembly ID	3
Resolution	2.527Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	128
Sequence identity between the two chains	0.98
PubMed citation	25356520

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	P23443	P23443
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4rloB	BioLiP:4rloA

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 4rlo-a3-m1-cB_4rlo-a3-m1-cA.pdb.gz

Full biological assembly Download: 4rlo-assembly3.cif.gz

Similar dimers

Other dimers with similar sequences and structures	3a60/1/1:B/1:A 4rlp/2/1:A/2:A
Other dimers with similar sequences but different poses	3wf8/2/1:A/2:A 3wf9/2/1:A/2:A