4rt7/1/1:A/2:A

Sequences

>4rt7-a1-m1-cA (length=274) [Search sequence]

YDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISGVSIQVAVKMLKDSSEREALMSELK
MMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKRNVLTFEDLLCFAYQVA
KGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMA
PESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATE
EIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADA

>4rt7-a1-m2-cA (length=274) [Search sequence]

Structure information

PDB ID	4rt7 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal Structure of FLT3 with a small molecule inhibitor
Assembly ID	1
Resolution	3.1Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	46
Sequence identity between the two chains	1.0
PubMed citation	25847190

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	A
UniProt accession	P36888	P36888
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4rt7A	BioLiP:4rt7A

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	4rt7-a1-m1-cA_4rt7-a1-m2-cA.pdb.gz

Full biological assembly

Download:

4rt7-assembly1.cif.gz