4uvr/1/1:A/2:A

Sequences

>4uvr-a1-m1-cA (length=439) [Search sequence]

GKLPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSR
FFSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQH
EVRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSL
IPAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKSDLLGGLLKAVYRDGTRMS
LHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMD
EMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNP
RLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDPDY
HTMVVGPTLNQCLVKYTRK

>4uvr-a1-m2-cA (length=439) [Search sequence]

Structure information

PDB ID	4uvr (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Binding mode, selectivity and potency of N-indolyl-oxopyridinyl-4- amino-propanyl-based inhibitors targeting Trypanosoma cruzi CYP51
Assembly ID	1
Resolution	2.48Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	33
Sequence identity between the two chains	1.0
PubMed citation	25393646

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	A
UniProt accession	Q7Z1V1	Q7Z1V1
Species	5693 (Trypanosoma cruzi)	5693 (Trypanosoma cruzi)
Function annotation	BioLiP:4uvrA	BioLiP:4uvrA

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

4uvr-a1-m1-cA_4uvr-a1-m2-cA.pdb.gz

Full biological assembly

Download:

4uvr-assembly1.cif.gz