4wis/1/1:A/1:B

Sequences
>4wis-a1-m1-cA (length=654) [Search sequence]
GVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVASPDLFAK
QVYRARLGDWLHGVRVSAPHNDIAQALQDEPVVEAERLRLIYLMITKPHNEWKHVESIFP
LHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGA
WLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAED
PITGEPVKVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPGKQYLG
FLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFT
AFVYIPFGHILHPFLNFWRATAQTLTFSEKELPTREFQINPARISNQMFYFTVTAQIVNF
ATEVVVPYIKQQAFQAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACC
FLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSNAS
PLKAWGLLLSILFAEHFYLVVQLAVRFVLSKLDSPGLQKERKERFQTKKRLLQENLGQDA
AAAPGIEHSEKITREALEEEARQASIEMFWQRQRGMQETIEIGRRMIEQQLAAG
>4wis-a1-m1-cB (length=654) [Search sequence]
GVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVASPDLFAK
QVYRARLGDWLHGVRVSAPHNDIAQALQDEPVVEAERLRLIYLMITKPHNEWKHVESIFP
LHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGA
WLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAED
PITGEPVKVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPGKQYLG
FLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFT
AFVYIPFGHILHPFLNFWRATAQTLTFSEKELPTREFQINPARISNQMFYFTVTAQIVNF
ATEVVVPYIKQQAFQAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACC
FLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSNAS
PLKAWGLLLSILFAEHFYLVVQLAVRFVLSKLDSPGLQKERKERFQTKKRLLQENLGQDA
AAAPGIEHSEKITREALEEEARQASIEMFWQRQRGMQETIEIGRRMIEQQLAAG
Structure information
PDB ID 4wis (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of the lipid scramblase nhTMEM16 in crystal form 1
Assembly ID 1
Resolution 3.3Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 245
Sequence identity between the two chains 1.0
PubMed citation 25383531
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession C7Z7K1 C7Z7K1
Species 660122 (Fusarium vanettenii 77-13-4) 660122 (Fusarium vanettenii 77-13-4)
Function annotation BioLiP:4wisA BioLiP:4wisB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4wis-a1-m1-cA_4wis-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 4wis-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 4wit/1/1:A/1:B 6qm4/1/1:A/1:B 6qm5/1/1:A/1:B 6qm6/1/1:A/1:B 6qm9/1/1:A/1:B 6qma/1/1:A/1:B 6qmb/1/1:A/1:B

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