4xi2/1/1:A/2:A

Sequences

>4xi2-a1-m1-cA (length=421) [Search sequence]

TELKKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAE DSIEMYEWYSKHMTRSQAEQLLEGGFIVRDYTVSVFAKGVIRHYVVCYYLAEKHLFSTIP ELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVV KYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY MANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVK VSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKM PYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMD E

>4xi2-a1-m2-cA (length=421) [Search sequence]

TELKKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAE DSIEMYEWYSKHMTRSQAEQLLEGGFIVRDYTVSVFAKGVIRHYVVCYYLAEKHLFSTIP ELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVV KYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY MANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVK VSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKM PYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMD E

Structure information

PDB ID	4xi2 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal Structure of an auto-inhibited form of Bruton's Tryrosine Kinase
Assembly ID	1
Resolution	2.6Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	255
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	A
UniProt accession	P35991	P35991
Species	10090 (Mus musculus)	10090 (Mus musculus)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 4xi2-a1-m1-cA_4xi2-a1-m2-cA.pdb.gz

Full biological assembly Download: 4xi2-assembly1.cif.gz