4yhj/1/1:B/1:A

Sequences

>4yhj-a1-m1-cB (length=490) [Search sequence]

GRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFL
DAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFE
ECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCAC
QVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVL
TIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRG
HIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHS
PFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVK
QHPVFKDINFRRLEANMLEPPFCPDPHAVYCGIYLDTADEDFYARFATGCVSIPWQNEMI
ESGCFKDINK

>4yhj-a1-m1-cA (length=501) [Search sequence]

Structure information

PDB ID	4yhj (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4 (GRK4)
Assembly ID	1
Resolution	2.6Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	140
Sequence identity between the two chains	0.996
PubMed citation	26134571

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	P32298	P32298
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4yhjB	BioLiP:4yhjA

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Color:	[By chain] [By residue index]
Spin:	[Spin off] [Spin on] [Reset]
Render:	[Low quality] [High quality]
Background:	[Black] [White]
Download:	4yhj-a1-m1-cB_4yhj-a1-m1-cA.pdb.gz

Full biological assembly

Color:	[By chain] [By residue index]
Spin:	[Spin off] [Spin on] [Reset]
Render:	[Low quality] [High quality]
Background:	[Black quality] [White quality]
Download:	4yhj-assembly1.cif.gz