4ywv/1/1:A/1:B

Sequences

>4ywv-a1-m1-cA (length=455) [Search sequence]

AYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDHLEERKAQLHQVANILRR DRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEFLMSTPLETDSGQAYYLKQS TGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAEAGSI TNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEEAGKNLKKTTLELGGDDAFIILDD ADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDPMDPETT LAPLSSAQAKADVLDQIKLALDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQEI FGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFINSGWTSL PELPFGGIKHSGYGRELSELGFTSFVNEHLIYIPN

>4ywv-a1-m1-cB (length=455) [Search sequence]

AYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDHLEERKAQLHQVANILRR DRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEFLMSTPLETDSGQAYYLKQS TGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAEAGSI TNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEEAGKNLKKTTLELGGDDAFIILDD ADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDPMDPETT LAPLSSAQAKADVLDQIKLALDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQEI FGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFINSGWTSL PELPFGGIKHSGYGRELSELGFTSFVNEHLIYIPN

Structure information

PDB ID	4ywv (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes
Assembly ID	1
Resolution	2.4Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	166
Sequence identity between the two chains	1.0
PubMed citation	25888791

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	A0A0J9X1M8	A0A0J9X1M8
Species	1010840 (Streptococcus pyogenes MGAS1882)	1010840 (Streptococcus pyogenes MGAS1882)
Function annotation	BioLiP:4ywvA	BioLiP:4ywvB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 4ywv-a1-m1-cA_4ywv-a1-m1-cB.pdb.gz

Full biological assembly Download: 4ywv-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

4ogd/1/1:A/1:B 4oht/1/1:A/1:B 4ywu/1/1:A/1:B