4zxb/1/1:E/2:E

Sequences

>4zxb-a1-m1-cE (length=800) [Search sequence]

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE KNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATQFVERCWTHSHCQ KVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQ DWRCVNFSFCQDLHHKCKCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLL EGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYA LVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLC LSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPP DFRDLLGFMLFYKEAPYQNVVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLV TFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLV FWERQAEDSELFELDYCLKGLKLPSRKELEESSFRKTFEDYLHEEHRPFEKVVNKESLVI SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHL MWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATS LAGNGSWTEPTYFYVTDYLD

>4zxb-a1-m2-cE (length=800) [Search sequence]

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE KNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATQFVERCWTHSHCQ KVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQ DWRCVNFSFCQDLHHKCKCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLL EGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYA LVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLC LSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPP DFRDLLGFMLFYKEAPYQNVVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLV TFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLV FWERQAEDSELFELDYCLKGLKLPSRKELEESSFRKTFEDYLHEEHRPFEKVVNKESLVI SGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHL MWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATS LAGNGSWTEPTYFYVTDYLD

Structure information

PDB ID	4zxb (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules
Assembly ID	1
Resolution	3.3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	149
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	E	E
UniProt accession	P06213	P06213
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 4zxb-a1-m1-cE_4zxb-a1-m2-cE.pdb.gz

Full biological assembly Download: 4zxb-assembly1.cif.gz