5eig/2/1:F/1:E

Sequences
>5eig-a2-m1-cF (length=381) [Search sequence]
GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGHSGFTYSRSGNPTRNCLEK
AVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKIS
FVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSP
YFQRPLALGADISMYSATYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYL
CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV
TFYIKGTLQHAEIFLKNLKLFTLAVSLGGFESLAELPAIMTHKNDRDVLGISDTLIRLSV
GLEDEEDLLEDLDQALKAAHP
>5eig-a2-m1-cE (length=384) [Search sequence]
GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGGFTYSRSGNPTRNCLEKAV
AALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV
DCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF
QRPLALGADISMYSATYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN
RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTF
YIKGTLQHAEIFLKNLKLFTLAVSLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRL
SVGLEDEEDLLEDLDQALKAAHPP
Structure information
PDB ID 5eig (database links: RCSB PDB PDBe PDBj PDBsum)
Title Engineered human cystathionine gamma lyase (E59T, E339V) to deplet cysteine
Assembly ID 2
Resolution 2.7Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 167
Sequence identity between the two chains 0.995
PubMed citation
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID F E
UniProt accession P32929 P32929
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:5eigF BioLiP:5eigE
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 5eig-a2-m1-cF_5eig-a2-m1-cE.pdb.gz
Full biological assembly
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Download: 5eig-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2nmp/1/1:C/1:D 3cog/1/1:C/1:D 5eig/1/1:A/1:B 5eig/1/1:D/1:C 5eig/2/1:H/1:G 5tsu/1/1:A/1:B 5tsu/1/1:D/1:C 5tsu/2/1:F/1:E 5tsu/2/1:G/1:H 6nba/1/1:A/1:B 6nba/1/1:D/1:C 6ovg/1/1:A/1:B 6ovg/1/1:D/1:C 6ovg/2/1:F/1:E 6ovg/2/1:H/1:G
Other dimers with similar sequences but different poses
  • 6ovg/2/1:E/1:G 2nmp/1/1:A/1:C 2nmp/1/1:B/1:D 3cog/1/1:A/1:C 3cog/1/1:B/1:D 5eig/1/1:A/1:C 5eig/1/1:B/1:D 5eig/2/1:E/1:G 5eig/2/1:F/1:H 5tsu/1/1:A/1:C 5tsu/1/1:D/1:B 5tsu/2/1:E/1:G 5tsu/2/1:F/1:H 6nba/1/1:A/1:C 6nba/1/1:B/1:D 6ovg/1/1:A/1:C 6ovg/1/1:B/1:D 6ovg/2/1:F/1:H
  • 6ovg/2/1:H/1:E 2nmp/1/1:A/1:D 2nmp/1/1:B/1:C 3cog/1/1:A/1:D 3cog/1/1:B/1:C 5eig/1/1:A/1:D 5eig/1/1:B/1:C 5eig/2/1:E/1:H 5eig/2/1:F/1:G 5tsu/1/1:A/1:D 5tsu/1/1:B/1:C 5tsu/2/1:E/1:H 5tsu/2/1:F/1:G 6nba/1/1:A/1:D 6nba/1/1:B/1:C 6ovg/1/1:A/1:D 6ovg/1/1:B/1:C 6ovg/2/1:F/1:G
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