5ex4/1/1:A/2:A |
| >5ex4-a1-m1-cA (length=462) [Search sequence] |
MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTV
PSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMP
VVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAM
NLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQT
AEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIA
NPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQ
VIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTEC
LGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD |
| >5ex4-a1-m2-cA (length=462) [Search sequence] |
MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTV
PSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMP
VVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAM
NLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQT
AEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIA
NPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQ
VIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTEC
LGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD |
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| PDB ID |
5ex4 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with tryptophan in all three allosteric binding sites |
| Assembly ID |
1 |
| Resolution |
2.25Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
86 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
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Chain 1 |
Chain 2 |
| Model ID |
1 |
2 |
| Chain ID |
A |
A |
| UniProt accession |
O53512 |
O53512 |
| Species |
1773 (Mycobacterium tuberculosis) |
1773 (Mycobacterium tuberculosis) |
| Function annotation |
BioLiP:5ex4A |
BioLiP:5ex4A |
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Switch viewer: [NGL] [JSmol]
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Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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| Other dimers with similar sequences and structures |
2w19/1/1:A/2:A 2w19/1/1:B/2:B 2w1a/1/1:A/2:A 2w1a/1/1:B/2:B 2ypo/1/1:A/2:A 2ypo/1/1:B/2:B 2ypp/1/1:A/2:A 2ypp/1/1:B/2:B 2ypq/1/1:A/2:A 2ypq/1/1:B/2:B 3kgf/1/1:A/2:A 3kgf/1/1:B/2:B 3nud/1/1:A/2:A 3nud/1/1:B/2:B 3nue/1/1:A/2:A 3nue/1/1:B/2:B 3nv8/1/1:A/2:A 3nv8/1/1:B/2:B 3pfp/1/1:A/2:A 3pfp/1/1:B/2:B 3rzi/1/1:A/2:A 3rzi/1/1:B/2:B 5ckv/1/1:A/2:A 5ckv/1/1:B/2:B 5ckx/1/1:A/2:A 5ckx/1/1:B/2:B 5e2l/1/1:A/2:A 5e2l/1/1:B/2:B 5e40/1/1:A/2:A 5e40/1/1:B/2:B 5e4n/1/1:A/2:A 5e4n/1/1:B/2:B 5e5g/1/1:A/2:A 5e5g/1/1:B/2:B 5e7z/1/1:A/2:A 5e7z/1/1:B/2:B 5ex4/1/1:B/2:B 6pbj/1/1:A/2:A |
| Other dimers with similar sequences but different poses |
3nv8/1/2:A/2:B 2b7o/1/1:A/1:B 2w19/1/1:B/1:A 2w19/1/2:B/2:A 2w1a/1/1:B/1:A 2w1a/1/2:B/2:A 2ypo/1/1:B/1:A 2ypo/1/2:B/2:A 2ypp/1/1:B/1:A 2ypp/1/2:B/2:A 2ypq/1/1:B/1:A 2ypq/1/2:B/2:A 3kgf/1/1:A/1:B 3kgf/1/2:A/2:B 3nud/1/1:A/1:B 3nud/1/2:A/2:B 3nue/1/1:B/1:A 3nue/1/2:B/2:A 3nv8/1/1:A/1:B 3pfp/1/1:A/1:B 3pfp/1/2:A/2:B 3rzi/1/1:A/1:B 3rzi/1/2:A/2:B 5ckv/1/1:A/1:B 5ckv/1/2:A/2:B 5ckx/1/1:A/1:B 5ckx/1/2:A/2:B 5e2l/1/1:B/1:A 5e2l/1/2:B/2:A 5e40/1/1:B/1:A 5e40/1/2:B/2:A 5e4n/1/1:B/1:A 5e4n/1/2:B/2:A 5e5g/1/1:B/1:A 5e5g/1/2:B/2:A 5e7z/1/1:B/1:A 5e7z/1/2:B/2:A 5ex4/1/1:A/1:B 5ex4/1/2:A/2:B 6pbj/1/1:B/1:A 6pbj/1/2:B/2:A |
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