5goa/1/1:C/1:D

Sequences

>5goa-a1-m1-cC (length=3423) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHSYSGMYLCCLSTSRKLAFDVGLQEDTTGEACW WTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPISSAQGY LIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWG QPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKEKLRKEVDGMGTSEIKY GDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFL FNRFIRGLDALSKKAKTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQN LFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSG SLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDV LCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDH TEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTV SSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVR FLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDT SQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQER NYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAE NAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRA EKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNE HYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVA QVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEV TRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDL VTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKL FPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSR ISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNH RVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMT EETKSITLFPDGLPGIGLSTSLRPRMQFSSPSFVSYSPEFPLDILKAKTIQMLTEAVQEG SLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSGLLQMKLPEPVKL QMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRDFHEDLMTHCGIELDLTIRGR LLSLVEKVTYTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTY TINGVSVEDTINLLASLGQIRSLLSVEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHET VMEVMVNVLGPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVTPLDVAAASVMD NNELALALREPDLEKVVRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIR RPEGLLAAMEEAIKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSLGDLVGVISIAFQFC PDHKAAMVLFLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLPLFAG TEHHASLIDSLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKL LTNHYERCWKYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPN FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPY KLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDVDAAHGYSPRAIDMSNVTLSRDLH AMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQI NGYAVSRGYFLSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTL DARTVMKTGLESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLED VQVSCYRILTSLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSPRHRAVNLFL QGYEKSWIETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYAD IMAKSCSFEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAIL NGGNSTVQQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKDDEFTCDLFRFLQ LLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQR NFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQ IELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLK DLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFV KREPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIE RVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQI IAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRILAI LHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINT QSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNSFL YLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYL YTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYE IYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDT VPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRK QYE

>5goa-a1-m1-cD (length=3423) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHSYSGMYLCCLSTSRKLAFDVGLQEDTTGEACW WTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPISSAQGY LIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWG QPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKEKLRKEVDGMGTSEIKY GDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFL FNRFIRGLDALSKKAKTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQN LFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSG SLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDV LCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDH TEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTV SSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVR FLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDT SQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQER NYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAE NAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRA EKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNE HYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVA QVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEV TRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDL VTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKL FPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSR ISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNH RVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMT EETKSITLFPDGLPGIGLSTSLRPRMQFSSPSFVSYSPEFPLDILKAKTIQMLTEAVQEG SLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSGLLQMKLPEPVKL QMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRDFHEDLMTHCGIELDLTIRGR LLSLVEKVTYTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTY TINGVSVEDTINLLASLGQIRSLLSVEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHET VMEVMVNVLGPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVTPLDVAAASVMD NNELALALREPDLEKVVRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIR RPEGLLAAMEEAIKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSLGDLVGVISIAFQFC PDHKAAMVLFLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLPLFAG TEHHASLIDSLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKL LTNHYERCWKYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPN FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPY KLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDVDAAHGYSPRAIDMSNVTLSRDLH AMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQI NGYAVSRGYFLSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTL DARTVMKTGLESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLED VQVSCYRILTSLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSPRHRAVNLFL QGYEKSWIETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYAD IMAKSCSFEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAIL NGGNSTVQQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKDDEFTCDLFRFLQ LLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQR NFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQ IELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLK DLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFV KREPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIE RVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQI IAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRILAI LHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINT QSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNSFL YLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYL YTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYE IYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDT VPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRK QYE

Structure information

PDB ID	5goa (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Cryo-EM structure of RyR2 in open state
Assembly ID	1
Resolution	4.2Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	115
Sequence identity between the two chains	1.0
PubMed citation	27708056

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	C	D
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:5goaC	BioLiP:5goaD

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 5goa-a1-m1-cC_5goa-a1-m1-cD.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 5goa-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

5go9/1/1:A/1:B 5go9/1/1:A/1:D 5go9/1/1:B/1:C 5go9/1/1:C/1:D 5goa/1/1:A/1:B 5goa/1/1:A/1:D 5goa/1/1:B/1:C