5j79/1/1:B/1:A |
| >5j79-a1-m1-cB (length=277) [Search sequence] |
AICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLRKDVLREAEILHKAR
FSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNY
LHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMGTIIYMPPENYEPGQSIKHDIY
SYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGW
AQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK |
| >5j79-a1-m1-cA (length=283) [Search sequence] |
NGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLRKDVLREAEILH
KARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALG
VNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMSAPEGGTIIYMPPENYEPS
IKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMIS
LIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK |
|
| PDB ID |
5j79 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
The identification and pharmacological characterization of 6-(tert-butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a highly potent and selective inhibitor of RIP2 Kinase, Compound 3 complex |
| Assembly ID |
1 |
| Resolution |
2.69Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
106 |
| Sequence identity between the two chains |
0.993 |
| PubMed citation |
27109867 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
B |
A |
| UniProt accession |
O43353 |
O43353 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:5j79B |
BioLiP:5j79A |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
|
|
|
|