5j8v/1/1:C/1:D

Sequences
>5j8v-a1-m1-cC (length=3453) [Search sequence]
QFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQ
SLSVRALQEMLANTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEAC
WWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTMQTLWNMNPICSCCEEGYVTGG
HVLGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLR
IRHVTTGRYLAQGLVVVDACKAHTKATSFCFRVGPPEIKYGESLCFVQHVASGLWLTYAI
LHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPLPIEAVILSLQD
LIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYA
GEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCV
LIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLP
GRELLLQTNLINYVTSIRPNIFVGGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPY
PGGGEGWGGNGVGDDLYSYLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRI
NGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGPIKEYRREGPRGPHLVGPSRCPPHL
ERIREKLAENIHELWALTRIPERNYNLQMSGETLKTLLALGTPAQTTLVDRLAENGHNVW
ARDRVAQVPYRLLDEATKRSNRDSLCQAVRTLLGYGRVRIFRAEKSYTVQSGRWYFEFEA
VTTGEMRVPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMDLTENT
IIFTLNGEVLAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFA
INMQRPVTTWFSKSLPQFEPVPPEHPHYLAHRTWGSQNSLVEMLFLRLSLPVQFYSVRVF
ACVWVGWVTPDYHQHDMNFDLSKVTDLVIGCLVGLMTFTANGKESNTFFQVEPNTKLFPA
VFVLPTHQNVIQFEAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGE
RLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVA
HALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPET
RAITLFPPGRKGGVTTSLRPPHHFIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQ
FVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVLQMKLPESVKLQMCNLLEYFCDQELQH
RVESLAAFAERYVDKLQANQRSRDFHQDLLAHCGIQLEPEEETSLSSRLRSLLETVRLSL
QELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMS
LLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNV
LGPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGLDVAAASVIDNNELALALQEQ
DLEKVVSYLAGCPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPGLLAAI
EEAIRIFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIVP
DHKASMVLFLDRVYFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLI
PLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMARPSMLQHLLRRLVFDVP
ILNKMPLKLLTNHYERCWKYYCLPTTSEEELHLTRKLFWGIFDSLYDQELYRMAMPCLCA
IAGALNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTH
PMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYDPREGYNPQPPDLSGVT
LSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQEL
LKFLQMNGYAVTRGYFLSTPAKVLGSGGHASNKEKEMIFCKLAALVRHRVSLFGTDAPAV
ILARSLDARTVMKSGPEIVKASASEDIEKMVENLRLGKTTVALLPVLTTLFQHIAQHQFL
DDVQVSCYRTLCSIYSLGTTVEKLRPALGECLARLAAAAFLEPQLNEYNACSTLPMLCSY
LPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNRIIVNNLGIDEATWMKRLAVSRARPEL
LHSHFIPTIGKRAGKVVAEEEQLRLEAKAEAEELYALYPLLIRYVDNNRAHWLTEPNANA
EELMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLKSKMAKAGDAQSGGTLKKMLPIG
LNMCAPFLQNNLHLQGKVEGSPSLRWQPTHRACNMFLESYKAAWILTEDHSFEDRMIDDL
SKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHSFEEKEMEKQRLLYQQSR
LHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFF
QSIQALMQTCSVLDLNAFERQNKAVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGN
TTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYI
QGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLS
LLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLIS
KKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTN
LSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQ
VKESKRQFIFDVVNEEKMELFVSFCEDTIFEMQIAAQISFWGELEVQRVKFLNYLSRNFY
TLRFLALFLAFAINFILLFVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPL
VIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKH
GDIFGRERIAELLGMLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAH
LLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDMM
TCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAF
GELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDE
TEHTGQESYVWKMYQERCWDFFPAGDCFRKQYE
>5j8v-a1-m1-cD (length=3453) [Search sequence]
QFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQ
SLSVRALQEMLANTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEAC
WWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTMQTLWNMNPICSCCEEGYVTGG
HVLGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLR
IRHVTTGRYLAQGLVVVDACKAHTKATSFCFRVGPPEIKYGESLCFVQHVASGLWLTYAI
LHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPLPIEAVILSLQD
LIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYA
GEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCV
LIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLP
GRELLLQTNLINYVTSIRPNIFVGGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPY
PGGGEGWGGNGVGDDLYSYLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRI
NGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGPIKEYRREGPRGPHLVGPSRCPPHL
ERIREKLAENIHELWALTRIPERNYNLQMSGETLKTLLALGTPAQTTLVDRLAENGHNVW
ARDRVAQVPYRLLDEATKRSNRDSLCQAVRTLLGYGRVRIFRAEKSYTVQSGRWYFEFEA
VTTGEMRVPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMDLTENT
IIFTLNGEVLAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFA
INMQRPVTTWFSKSLPQFEPVPPEHPHYLAHRTWGSQNSLVEMLFLRLSLPVQFYSVRVF
ACVWVGWVTPDYHQHDMNFDLSKVTDLVIGCLVGLMTFTANGKESNTFFQVEPNTKLFPA
VFVLPTHQNVIQFEAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGE
RLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVA
HALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPET
RAITLFPPGRKGGVTTSLRPPHHFIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQ
FVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVLQMKLPESVKLQMCNLLEYFCDQELQH
RVESLAAFAERYVDKLQANQRSRDFHQDLLAHCGIQLEPEEETSLSSRLRSLLETVRLSL
QELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMS
LLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNV
LGPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGLDVAAASVIDNNELALALQEQ
DLEKVVSYLAGCPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPGLLAAI
EEAIRIFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIVP
DHKASMVLFLDRVYFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLI
PLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMARPSMLQHLLRRLVFDVP
ILNKMPLKLLTNHYERCWKYYCLPTTSEEELHLTRKLFWGIFDSLYDQELYRMAMPCLCA
IAGALNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTH
PMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYDPREGYNPQPPDLSGVT
LSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQEL
LKFLQMNGYAVTRGYFLSTPAKVLGSGGHASNKEKEMIFCKLAALVRHRVSLFGTDAPAV
ILARSLDARTVMKSGPEIVKASASEDIEKMVENLRLGKTTVALLPVLTTLFQHIAQHQFL
DDVQVSCYRTLCSIYSLGTTVEKLRPALGECLARLAAAAFLEPQLNEYNACSTLPMLCSY
LPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNRIIVNNLGIDEATWMKRLAVSRARPEL
LHSHFIPTIGKRAGKVVAEEEQLRLEAKAEAEELYALYPLLIRYVDNNRAHWLTEPNANA
EELMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLKSKMAKAGDAQSGGTLKKMLPIG
LNMCAPFLQNNLHLQGKVEGSPSLRWQPTHRACNMFLESYKAAWILTEDHSFEDRMIDDL
SKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHSFEEKEMEKQRLLYQQSR
LHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFF
QSIQALMQTCSVLDLNAFERQNKAVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGN
TTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYI
QGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLS
LLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLIS
KKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTN
LSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQ
VKESKRQFIFDVVNEEKMELFVSFCEDTIFEMQIAAQISFWGELEVQRVKFLNYLSRNFY
TLRFLALFLAFAINFILLFVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPL
VIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKH
GDIFGRERIAELLGMLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAH
LLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDMM
TCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAF
GELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDE
TEHTGQESYVWKMYQERCWDFFPAGDCFRKQYE
Structure information
PDB ID 5j8v (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structure of rabbit ryanodine receptor RyR1 open state activated by calcium ion
Assembly ID 1
Resolution 4.9Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 147
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID C D
UniProt accession P11716 P11716
Species 9986 (Oryctolagus cuniculus) 9986 (Oryctolagus cuniculus)
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 5j8v-a1-m1-cC_5j8v-a1-m1-cD.pdb.gz
Full biological assembly
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black quality]   [White quality]  
Download: 5j8v-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 5j8v/1/1:A/1:B 5j8v/1/1:A/1:D 5j8v/1/1:B/1:C

[Back to Home]