5khm/1/1:A/1:B

Sequences

>5khm-a1-m1-cA (length=126) [Search sequence]

MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIK TPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKIN ELPTEE

>5khm-a1-m1-cB (length=126) [Search sequence]

SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKII KTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI NELPTE

Structure information

PDB ID	5khm (database links: RCSB PDB PDBe PDBj PDBsum)
Title	The first BET bromodomain of BRD4 bound to compound 13 in a bivalent manner
Assembly ID	1
Resolution	1.48Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	13
Sequence identity between the two chains	0.992
PubMed citation	27528113

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	O60885	O60885
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:5khmA	BioLiP:5khmB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 5khm-a1-m1-cA_5khm-a1-m1-cB.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 5khm-assembly1.cif.gz