5las/1/1:B/1:A

Sequences

>5las-a1-m1-cB (length=211) [Search sequence]

ALKLALEYIVPAMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSK
DIRGDKITWIEGKEPGCETIGLLMSSMDDLICHCNGKLGSYKINGRTKAMVACYPGNGTG
YVRHVDNCNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSD
RRNPHEVQPAYATRYAITVWYFDADETAAAK

>5las-a1-m1-cA (length=215) [Search sequence]

PALKLALEYIVPAMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSS
KDIRGDKITWIEGKEPGCETIGLLMSSMDDLICHCNGKLGSYKINGRTKAMVACYPGNGT
GYVRHVDNCNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWS
DRRNPHEVQPAYATRYAITVWYFDADETAAAKVKY

Structure information

PDB ID	5las (database links: RCSB PDB PDBe PDBj PDBsum)
Title	HIF prolyl hydroxylase 2 (PHD2-R281C/P317C/R396T) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-3)
Assembly ID	1
Resolution	2.1Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	53
Sequence identity between the two chains	1.0
PubMed citation	27561929

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	Q9GZT9	Q9GZT9
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:5lasB	BioLiP:5lasA

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

5las-a1-m1-cB_5las-a1-m1-cA.pdb.gz

Full biological assembly

Download:

5las-assembly1.cif.gz