5ly2/1/1:C/1:B

Sequences
>5ly2-a1-m1-cC (length=342) [Search sequence]
SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD
LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN
LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEGVNTPYLYFGMWKTSFAWHTEDM
DLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKK
YGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDM
VKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFL
>5ly2-a1-m1-cB (length=345) [Search sequence]
PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA
PIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNP
PIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHT
EDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLM
LKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCR
KDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFL
Structure information
PDB ID 5ly2 (database links: RCSB PDB PDBe PDBj PDBsum)
Title JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Macrocyclic PEPTIDE Inhibitor CP2_R6Kme3 (13-mer)
Assembly ID 1
Resolution 2.43Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 30
Sequence identity between the two chains 0.985
PubMed citation 28382930
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID C B
UniProt accession O75164 O75164
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:5ly2C BioLiP:5ly2B
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 5ly2-a1-m1-cC_5ly2-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 5ly2-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 5ly2/1/1:C/1:A 5fwe/1/1:D/1:B 5ly1/1/1:C/1:A
  • 5ly2/1/1:B/1:A 5ly1/1/1:B/1:A 5ly1/1/1:C/1:D 5ly2/1/1:C/1:D 7eqv/1/1:A/2:A
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