5s8a/1/1:A/2:B

Sequences

>5s8a-a1-m1-cA (length=283) [Search sequence]

RTVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHEN ILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHI EIFGGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHRVGTKRYMAPEVLDETIQVDCF DSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPN IPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID

>5s8a-a1-m2-cB (length=292) [Search sequence]

ARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILG FIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIF GKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVL DETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKV VCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID

Structure information

PDB ID	5s8a (database links: RCSB PDB PDBe PDBj PDBsum)
Title	XChem group deposition -- Crystal Structure of human ACVR1 in complex with NU074484b
Assembly ID	1
Resolution	1.3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	71
Sequence identity between the two chains	0.986
PubMed citation

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	B
UniProt accession	Q04771	Q04771
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:5s8aA	BioLiP:5s8aB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 5s8a-a1-m1-cA_5s8a-a1-m2-cB.pdb.gz

Full biological assembly Download: 5s8a-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	3q4u/1/1:A/1:B 3q4u/2/1:C/2:D 3q4u/3/3:C/1:D 5s7k/1/1:A/2:B 5s7l/1/1:A/2:B 5s7q/1/1:A/2:B 5s7t/1/1:A/2:B 5s7w/1/1:A/2:B 5s83/1/1:A/2:B 5s86/1/1:A/2:B 5s8b/1/1:A/2:B 5s9k/1/1:A/2:B
Other dimers with similar sequences but different poses	3oom/1/1:A/2:A 4dym/1/1:A/2:A