5tia/1/1:C/1:D

Sequences

>5tia-a1-m1-cC (length=323) [Search sequence]

GLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQ NGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQF RLLENKIGVLYRDNFKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKN ITRGLEEEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPF QLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHYLRSTVSDRYKVFVDLFNL STYLIPRHWIPKMNPTIHKFLEH

>5tia-a1-m1-cD (length=349) [Search sequence]

GLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQ NGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQF RLLENKIGVLQNMRVPYNRRHYRDNFKGEENELLLKSEQEKTLLELVEAWLERTPGLEPH GFNFWGKLEKNITRGLEEEFIRIQAEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGER RLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGT GGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLEH

Structure information

PDB ID	5tia (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of human TDO in complex with Trp, Northeast Structural Genomics Consortium Target HR6161
Assembly ID	1
Resolution	2.441Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	160
Sequence identity between the two chains	1.0
PubMed citation	27762317

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	C	D
UniProt accession	P48775	P48775
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:5tiaC	BioLiP:5tiaD

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 5tia-a1-m1-cC_5tia-a1-m1-cD.pdb.gz

Full biological assembly Download: 5tia-assembly1.cif.gz