5u6c/1/1:B/1:A

Sequences
>5u6c-a1-m1-cB (length=257) [Search sequence]
NKLEDVVIDRNLLILGKILGEGSVMEGNLKQEDGTSLKVAVKTMIEEFLSEAACMKDFSH
PNVMRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVD
IALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFMPVKWIAIESLADRVYTSKSDVWA
FGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRP
TFSVLRLQLEKLLESLP
>5u6c-a1-m1-cA (length=272) [Search sequence]
ELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQREI
EEFLSEAACMKDFSHPNVMRLLGVCIEMIPKPMVILPFMKYGDLHTYLLYSRLETGPKHI
PLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSPVKWIAIESL
ADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEI
MYSCWRTDPLDRPTFSVLRLQLEKLLESLPDV
Structure information
PDB ID 5u6c (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of the Mer kinase domain in complex with a macrocyclic inhibitor
Assembly ID 1
Resolution 2.1Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 52
Sequence identity between the two chains 0.981
PubMed citation 28724631
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession Q12866 Q12866
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:5u6cB BioLiP:5u6cA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 5u6c-a1-m1-cB_5u6c-a1-m1-cA.pdb.gz
Full biological assembly
Download: 5u6c-assembly1.cif.gz
Similar dimers

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