5xyz/1/1:A/1:B

Sequences
>5xyz-a1-m1-cA (length=230) [Search sequence]
SWEIDPKDLTFLKELVKYGKWRGQYDVAIKMIKMSDEEEAKVMMNLSHEKLVQLYGVCTK
QRPIFIITEYMANGCLLNYLRERFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLV
NDQGVVKVSDFGLSRFPVRWSPPEVLMFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSET
AEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD
>5xyz-a1-m1-cB (length=234) [Search sequence]
SWEIDPKDLTFLKELVKYGKWRGQYDVAIKMIKMSEDEIEEAKVMMNLSHEKLVQLYGVC
TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAA
RNCLVNDQGVVKVSDFGLSRFPVRWSPPEVLMSSKSDIWAFGVLMWEIYSLGKMPYERFT
NSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD
Structure information
PDB ID 5xyz (database links: RCSB PDB PDBe PDBj PDBsum)
Title The structure of human BTK kinase domain in complex with a covalent inhibitor
Assembly ID 1
Resolution 2.64Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 38
Sequence identity between the two chains 0.987
PubMed citation 28945083
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession Q06187 Q06187
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:5xyzA BioLiP:5xyzB
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 5xyz-a1-m1-cA_5xyz-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 5xyz-assembly1.cif.gz

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