5yt3/2/1:C/1:D |
| >5yt3-a2-m1-cC (length=288) [Search sequence] |
LELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLI
HAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQ
ILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGSYMSPERLYSVQSD
IWSMGLSLVEMAVGRYPIPPPDAKELELMFGCPMAIFELLDYIVNEPPPKLPSGVFSLEF
QDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLN |
| >5yt3-a2-m1-cD (length=309) [Search sequence] |
ELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKL
IHLKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR
IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDDMA
NDFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFAIFEL
LDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAG
WLCSTIGLN |
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| PDB ID |
5yt3 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant |
| Assembly ID |
2 |
| Resolution |
2.9Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
123 |
| Sequence identity between the two chains |
0.986 |
| PubMed citation |
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Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
C |
D |
| UniProt accession |
Q02750 |
Q02750 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:5yt3C |
BioLiP:5yt3D |
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Switch viewer: [NGL] [JSmol]
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Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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| Other dimers with similar sequences but different poses |
3dv3/1/1:A/2:A 1s9j/1/1:A/2:A 2p55/1/1:A/2:A 3e8n/2/1:A/2:A 3eqb/1/1:A/2:A 3mbl/1/1:A/2:A 4ark/1/1:A/2:A 4lmn/2/1:A/2:A
3wig/2/1:A/2:A 3orn/2/1:A/2:A |
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