6a4i/1/1:D/1:B

Sequences
>6a4i-a1-m1-cD (length=290) [Search sequence]
LIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQN
GHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFR
LLENKIGVLKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEEVLLSLFD
EKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHV
CMVHRMLGSKYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHK
>6a4i-a1-m1-cB (length=309) [Search sequence]
LIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQN
GHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFR
LLENKIGVLKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLE
EEFQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQ
LLTSLMDIDSLMTKWRYNHVCMVHRMLGSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHW
IPKMNPTIH
Structure information
PDB ID 6a4i (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal Structure of human TDO inhibitor complex
Assembly ID 1
Resolution 2.65Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 51
Sequence identity between the two chains 0.993
PubMed citation
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID D B
UniProt accession P48775 P48775
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6a4iD BioLiP:6a4iB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6a4i-a1-m1-cD_6a4i-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 6a4i-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 6a4i/1/1:B/1:C 4pw8/2/1:F/1:G
  • 6ud5/1/1:C/1:D 4pw8/2/1:H/1:G
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