6aah/1/1:A/1:B

Sequences

>6aah-a1-m1-cA (length=283) [Search sequence]

VDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPHIADLKKEIEIL
RNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICK
GMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKETVKDDRDSPVFWYAPE
CLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEG
KRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK

>6aah-a1-m1-cB (length=284) [Search sequence]

VDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPNHIADLKKEIEI
LRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQIC
KGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKETVKDDRDSPVFWYAP
ECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKE
GKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK

Structure information

PDB ID	6aah (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of JAK1 in complex with peficitinib
Assembly ID	1
Resolution	1.83Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	20
Sequence identity between the two chains	1.0
PubMed citation	30145050

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P23458	P23458
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6aahA	BioLiP:6aahB

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	6aah-a1-m1-cA_6aah-a1-m1-cB.pdb.gz

Full biological assembly

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Download:	6aah-assembly1.cif.gz