6aak/2/1:D/1:C

Sequences

>6aak-a2-m1-cD (length=266) [Search sequence]

PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQ ILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGME YLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDVVSPIFWYAPESLSDNIFS RQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMPALSRLLELLEEGQRLPAPPACPAEVHE LMKLCWAPSPQDRPSFSALGPQLDML

>6aak-a2-m1-cC (length=274) [Search sequence]

PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQ ILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGME YLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDVVREPGQSPIFWYAPESLS DNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGPALSRLLELLEEGQRLPAPPA CPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLW

Structure information

PDB ID	6aak (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of JAK3 in complex with peficitinib
Assembly ID	2
Resolution	2.67Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	39
Sequence identity between the two chains	1.0
PubMed citation	30145050

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	D	C
UniProt accession	P52333	P52333
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6aakD	BioLiP:6aakC

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 6aak-a2-m1-cD_6aak-a2-m1-cC.pdb.gz

Full biological assembly Download: 6aak-assembly2.cif.gz

Similar dimers