6e2o/1/1:B/1:A

Sequences
>6e2o-a1-m1-cB (length=250) [Search sequence]
LEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPESQPLHEEIALHKHLKHK
NIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLH
DNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLTGTLQYMAPEIIDKYGKAADIWSLGC
TIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACA
NDLLVDEFLK
>6e2o-a1-m1-cA (length=263) [Search sequence]
LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPESRYSQPLHEEIALHKH
LKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGL
KYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLACTEFTGTLQYMAPEIIDKGPR
GYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFIL
KCFEPDPDKRACANDLLVDEFLK
Structure information
PDB ID 6e2o (database links: RCSB PDB PDBe PDBj PDBsum)
Title ASK1 kinase domain complex with inhibitor
Assembly ID 1
Resolution 2.389Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 60
Sequence identity between the two chains 1.0
PubMed citation 30024858
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession Q99683 Q99683
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6e2oB BioLiP:6e2oA
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6e2o-a1-m1-cB_6e2o-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 6e2o-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2clq/1/1:A/2:A 2clq/2/1:B/3:B 6e2m/1/1:B/1:A 6e2n/1/1:B/1:A 6oyt/2/1:B/1:D 6oyw/1/1:C/2:A 6oyw/2/1:B/3:D

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