6fcx/1/1:B/1:A |
| >6fcx-a1-m1-cB (length=590) [Search sequence] |
RHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGD
PGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDP
FNYAVDLVKHIRSEFGDYFDICVAGYPKGHPGSFEADLKHLKEKVSADFIITQLFFEADT
FFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIR
NYGIELAVSLCQELLASGGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRR
EEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELL
KMWGEELTSEASVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQG
ILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNY
HLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKL
YEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNAENL |
| >6fcx-a1-m1-cA (length=596) [Search sequence] |
ERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAG
DPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGD
PFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLF
FEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDN
DAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWA
LSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNFGELKDYYLFYLKSKSPKE
ELLKMWGEELTSEASVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVN
RQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELR
VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNAENLYFQ |
|
| PDB ID |
6fcx (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Structure of human 5,10-methylenetetrahydrofolate reductase (MTHFR) |
| Assembly ID |
1 |
| Resolution |
2.5Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
83 |
| Sequence identity between the two chains |
0.992 |
| PubMed citation |
29891918 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
B |
A |
| UniProt accession |
P42898 |
P42898 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:6fcxB |
BioLiP:6fcxA |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
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