6g31/1/1:E/1:F

Sequences

>6g31-a1-m1-cE (length=249) [Search sequence]

QETVQRILLEPYKYLLQLAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRG
FPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHQDAVKLFTRQLLELHQGQGLDIYWRDN
YTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKNTLGLFFQIRYDYANLHSFCEDLTE
GKFSFPTIHAIWSRPTQVQNILRQRTENIDIKKYCVHYGSFEYTRNTLKELEAKPELVAL
VKHLSKMFK

>6g31-a1-m1-cF (length=285) [Search sequence]

ETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDD
IEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHQDAVKLFTRQLLELHQG
QGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQ
IRYDYANLHSKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYL
EDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFK

Structure information

PDB ID	6g31 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate
Assembly ID	1
Resolution	3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	112
Sequence identity between the two chains	0.996
PubMed citation	30275041

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	E	F
UniProt accession	O95749	O95749
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6g31E	BioLiP:6g31F

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

6g31-a1-m1-cE_6g31-a1-m1-cF.pdb.gz

Full biological assembly

Download:

6g31-assembly1.cif.gz