6gfe/1/1:K/1:H

Sequences

>6gfe-a1-m1-cK (length=426) [Search sequence]

QVELQQSGPGLVKPSQTLSLTCAISGDSVSSRSASWSWIRQSPGRGLEWLGRTYYRSHWY YEYAQSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCARMDVPSFRYFDVWGQGTLVT VSSASTKGPSVFPLAPCSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGL YSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESGPSVFLFPPKPKDTLMISRTPE VTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKE YKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIA VEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQ KSLSLS

>6gfe-a1-m1-cH (length=429) [Search sequence]

QVELQQSGPGLVKPSQTLSLTCAISGDSVSSRSASWSWIRQSPGRGLEWLGRTYYRSHWY YEYAQSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCARMDVPSFRYFDVWGQGTLVT VSSASTKGPSVFPLAPCSSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSS GLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKGPSVFLFPPKPKDTLMISR TPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLN GKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPS DIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNH YTQKSLSLS

Structure information

PDB ID	6gfe (database links: RCSB PDB PDBe PDBj PDBsum)
Title	High-resolution Structure of a therapeutic full-length anti-NPRA Antibody with exceptional Conformational Diversity
Assembly ID	1
Resolution	1.8Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	66
Sequence identity between the two chains	1.0
PubMed citation	31023536

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	K	H
UniProt accession
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6gfeK	BioLiP:6gfeH

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 6gfe-a1-m1-cK_6gfe-a1-m1-cH.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 6gfe-assembly1.cif.gz