6gin/1/1:A/1:B

Sequences

>6gin-a1-m1-cA (length=296) [Search sequence]

VARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENIL
GFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEI
FGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMA
PEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFED
MRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID

>6gin-a1-m1-cB (length=296) [Search sequence]

Structure information

PDB ID	6gin (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group.
Assembly ID	1
Resolution	2.2Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	34
Sequence identity between the two chains	1.0
PubMed citation	30085668

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	Q04771	Q04771
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6ginA	BioLiP:6ginB

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	6gin-a1-m1-cA_6gin-a1-m1-cB.pdb.gz

Full biological assembly

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Download:	6gin-assembly1.cif.gz