6gwr/1/1:B/1:A

Sequences

>6gwr-a1-m1-cB (length=285) [Search sequence]

RVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSPLLVAVKILRPDATKNARNDFLKE
VKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAGPTISYPML
LHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRA
VLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRD
QGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAED

>6gwr-a1-m1-cA (length=300) [Search sequence]

MPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLGHPLLVAVKILRPDATK
NARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAA
EQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLY
AGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQ
VIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNT

Structure information

PDB ID	6gwr (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of the kinase domain of human DDR1 in complex with a potent and selective inhibitor of DDR1 and DDR2
Assembly ID	1
Resolution	2.07Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	33
Sequence identity between the two chains	1.0
PubMed citation	30075624

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	Q08345	Q08345
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6gwrB	BioLiP:6gwrA

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

6gwr-a1-m1-cB_6gwr-a1-m1-cA.pdb.gz

Full biological assembly

Download:

6gwr-assembly1.cif.gz