6jg3/1/1:B/1:D

Sequences

>6jg3-a1-m1-cB (length=3477) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAF DVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQ TLWSVAPISSGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSL WRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSS KEKRKEVDGMGTSEIKYGDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRS QHEESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLQDLIGYFHPPDE HLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLY ELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHI KSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSS MRPNIFLGKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDL FSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENF NIDGLFFPVVSFSAGIKVRFLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTY TRDLLGPTVSAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDD NKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMD LSFIKLTPSQEAMVDKLAENAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAV RTLLGYGYNLEARFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSD ERAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELA FKDFDVGDGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWL SKRLPQFLQVPSSHEHIEVTRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPN VWVGWITSDFHQYDTAFDLVTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTF TANGKDLSTYYQVEPSTKLFPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFL SHVLWSRMPNQFLKVDVSRISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELL KFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHL SSYATARLMMNNEFIVPMTEETKSITLFPDGLPGIGLSTSLRPRMQFSSPSNECYQYSPE FPLDILKAKTIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKH ILQLIEPSGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFR YNEVRDQLLDFHEDLMTHCGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVRWAQES VIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVR MGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANCCRFLC YFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPD LEKVVRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEA IKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSGDLVGVISIAFQFCPDHKAAMVLFLDR VYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLLFAGTEHHASLIDSLLHT VKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCWKYYCL PGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTSNITIP EKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWP IKESLKTMLAWGWRIERTREGDVDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIW AKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYFLSAA SRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGLESVK FLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILTSLYA LGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSPRHRAVNLFLQGYEKSWIETEEHY FEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCSFEEKEME KQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLEY LKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQLLCEGHN SDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQ VAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKEL MDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDT FKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPA KDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFE ISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQIIAYQQ KLLNYFARNFYNMRMLALFVAFAINFILLFYKVVHYVLEESSGYMEPTLRILAILHTVIS FFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNN YWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYM TMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAF NFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIF DITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFE THTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYE

>6jg3-a1-m1-cD (length=3477) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAF DVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQ TLWSVAPISSGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSL WRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSS KEKRKEVDGMGTSEIKYGDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRS QHEESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLQDLIGYFHPPDE HLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLY ELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHI KSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSS MRPNIFLGKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDL FSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENF NIDGLFFPVVSFSAGIKVRFLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTY TRDLLGPTVSAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDD NKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMD LSFIKLTPSQEAMVDKLAENAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAV RTLLGYGYNLEARFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSD ERAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELA FKDFDVGDGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWL SKRLPQFLQVPSSHEHIEVTRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPN VWVGWITSDFHQYDTAFDLVTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTF TANGKDLSTYYQVEPSTKLFPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFL SHVLWSRMPNQFLKVDVSRISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELL KFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHL SSYATARLMMNNEFIVPMTEETKSITLFPDGLPGIGLSTSLRPRMQFSSPSNECYQYSPE FPLDILKAKTIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKH ILQLIEPSGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFR YNEVRDQLLDFHEDLMTHCGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVRWAQES VIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVR MGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANCCRFLC YFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPD LEKVVRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEA IKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSGDLVGVISIAFQFCPDHKAAMVLFLDR VYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLLFAGTEHHASLIDSLLHT VKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCWKYYCL PGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTSNITIP EKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWP IKESLKTMLAWGWRIERTREGDVDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIW AKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYFLSAA SRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGLESVK FLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILTSLYA LGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSPRHRAVNLFLQGYEKSWIETEEHY FEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCSFEEKEME KQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLEY LKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQLLCEGHN SDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQ VAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKEL MDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDT FKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPA KDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFE ISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQIIAYQQ KLLNYFARNFYNMRMLALFVAFAINFILLFYKVVHYVLEESSGYMEPTLRILAILHTVIS FFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNN YWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYM TMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAF NFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIF DITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFE THTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYE

Structure information

PDB ID	6jg3 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Cryo-EM structure of RyR2 (Ca2+ alone dataset)
Assembly ID	1
Resolution	6.1Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	119
Sequence identity between the two chains	1.0
PubMed citation	31792195

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	D
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:6jg3B	BioLiP:6jg3D

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 6jg3-a1-m1-cB_6jg3-a1-m1-cD.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 6jg3-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6jg3/1/1:A/1:C 6jg3/1/1:A/1:D 6jg3/1/1:B/1:C