6jgz/1/1:F/1:H

Sequences

>6jgz-a1-m1-cF (length=3485) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAF DVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQ TLWSVAPISSGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSL WRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSS KEKRKEVDGMGTSEIKYGDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRS QHEESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLQDLIGYFHPPDE HLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLY ELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHI KSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSS MRPNIFLGKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDL FSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENF NIDGLFFPVVSFSAGIKVRFLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTY TRDLLGPTVSAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDD NKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMD LSFIKLTPSQEAMVDKLAENAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAV RTLLGYGYNLEARFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSD ERAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELA FKDFDVGDGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWL SKRLPQFLQVPSSHEHIEVTRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPN VWVGWITSDFHQYDTAFDLVTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTF TANGKDLSTYYQVEPSTKLFPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFL SHVLWSRMPNQFLKVDVSRISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELL KFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHL SSYATARLMMNNEFIVPMTEETKSITLFPDGLPGIGLSTSLRPRMQFSSPSFVSINNECY QYSPEFPLDILKAKTIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHN EDLKHILQLIEPSGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQD NQRFRYNEVRDQLLDFHEDLMTHCGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVR WAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRS LLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANC CRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALA LREPDLEKVVRYLAGCGPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAA MEEAIKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSGDLVGVISIAFQFCPDHKAAMVL FLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLPLFAGTEHHASLID SLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCW KYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTS NITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKE IYRWPIKESLKTMLAWGWRIERTREGDDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENY HNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYF LSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGL ESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILT SLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSYNLPRHRAVNLFLQGYEKSW IETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCS FEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTV QQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQ LLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQR NFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQ IELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLK DLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFV KRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKR IERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAA QIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRIL AILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVI NTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNS FLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVV YLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDE YEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYF DTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCF RKQYE

>6jgz-a1-m1-cH (length=3485) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAF DVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQ TLWSVAPISSGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSL WRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSS KEKRKEVDGMGTSEIKYGDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRS QHEESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLQDLIGYFHPPDE HLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLY ELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHI KSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSS MRPNIFLGKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDL FSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENF NIDGLFFPVVSFSAGIKVRFLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTY TRDLLGPTVSAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDD NKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMD LSFIKLTPSQEAMVDKLAENAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAV RTLLGYGYNLEARFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSD ERAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELA FKDFDVGDGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWL SKRLPQFLQVPSSHEHIEVTRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPN VWVGWITSDFHQYDTAFDLVTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTF TANGKDLSTYYQVEPSTKLFPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFL SHVLWSRMPNQFLKVDVSRISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELL KFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHL SSYATARLMMNNEFIVPMTEETKSITLFPDGLPGIGLSTSLRPRMQFSSPSFVSINNECY QYSPEFPLDILKAKTIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHN EDLKHILQLIEPSGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQD NQRFRYNEVRDQLLDFHEDLMTHCGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVR WAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRS LLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANC CRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALA LREPDLEKVVRYLAGCGPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAA MEEAIKIGNAIMTFYAALIDLLGRCAEAIRIRSILRSGDLVGVISIAFQFCPDHKAAMVL FLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLPLFAGTEHHASLID SLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCW KYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTS NITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKE IYRWPIKESLKTMLAWGWRIERTREGDDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENY HNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYF LSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGL ESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILT SLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSYNLPRHRAVNLFLQGYEKSW IETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCS FEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTV QQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQ LLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQR NFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQ IELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLK DLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFV KRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKR IERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAA QIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRIL AILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVI NTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGSAVLNSIDVKYQMWKLGVVFTDNS FLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVV YLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDE YEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYF DTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCF RKQYE

Structure information

PDB ID	6jgz (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of RyR2 (F/P/Ca2+ dataset)
Assembly ID	1
Resolution	4.6Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	158
Sequence identity between the two chains	1.0
PubMed citation	31792195

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	F	H
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:6jgzF	BioLiP:6jgzH

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 6jgz-a1-m1-cF_6jgz-a1-m1-cH.pdb.gz

Full biological assembly Download: 6jgz-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6jgz/1/1:B/1:D 6jgz/1/1:B/1:H 6jgz/1/1:D/1:F