6jh6/1/1:F/1:H

Sequences

>6jh6-a1-m1-cF (length=3454) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTT GEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPIS SGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVA WSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKDGMGTSEI KYGDSVCFIQHIGTGLWLTYQSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVF LFNRFIRGLDALSKKALPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQ EEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSGSLD WLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCS LCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDHTEP FVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSSP NQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLL GEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDTSQI VLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYN LQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAH NVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRAEKT YAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNEHYG RSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVAQVG RMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEVTRI DVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDLVTV TLGDEKGKVHESIKRSNYMVCANNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKLFPAV FAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISER QGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAH ALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETK SITLFPDGLPGIGLSTSLRPRMQFSSPSFVSINNECYQYSPEFPLDILKAKTIQMLTEAV QEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSGLLQMKLPEP VKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVRDQLLDFHEDLMTH CGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQ YDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMN NKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANCCRFLCYFCRISRQNQKAMFDHLS YLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGPVEGER YLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEAIKIGNAIMTFYAALIDLLG RCAEAIRIRSILRSLGDLVGVISIAFQFCPDHKAAMVLFLDRVYVQDFLLHLLGFLPDLR AAASLTDMALALNRYLCTAVLPLLLFAGTEHHASLIDSLLHTVKGCSLTKAQRDSIEVCL LSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCWKYYCLPGGASEEELHLSRKLFWG IFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKW SMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERT REGDDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLL VPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYFLSAASRPLCSGGHASNKEKEMVF CKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGLESVKFLDNAAEDLEKTMENLKQG QFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILTSLYALGTSVERQRSALGECLAAF AGAAFLETHLDKHNIYSYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPRVDP LHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCSFEEKEMEKQKLLYQQARLHDRGA AEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLEYLKEKKDVGFFQSLAGL MQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTT VNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGP CTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLE GNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRD FHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSE HMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKE SKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQIIAYQQKLLNYFARNFYNMRML ALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLV IFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYG EFYGRDRISELLGVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMG FKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDM LTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDA FGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKD ETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYE

>6jh6-a1-m1-cH (length=3454) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANTGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTT GEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPIS SGSEAAQGYLIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVA WSGSHIRWGQPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKDGMGTSEI KYGDSVCFIQHIGTGLWLTYQSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVF LFNRFIRGLDALSKKALPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQ EEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSGSLD WLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCS LCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDHTEP FVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSSP NQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLL GEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDTSQI VLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYN LQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAH NVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRAEKT YAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNEHYG RSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVAQVG RMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEVTRI DVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDLVTV TLGDEKGKVHESIKRSNYMVCANNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKLFPAV FAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISER QGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAH ALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETK SITLFPDGLPGIGLSTSLRPRMQFSSPSFVSINNECYQYSPEFPLDILKAKTIQMLTEAV QEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSGLLQMKLPEP VKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVRDQLLDFHEDLMTH CGIELDSDLTIRGRLLSLVEKVTYLTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQ YDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMN NKVFYQHPNLMRALGMHETVMEVMVNVLGFPKMVANCCRFLCYFCRISRQNQKAMFDHLS YLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGPVEGER YLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEAIKIGNAIMTFYAALIDLLG RCAEAIRIRSILRSLGDLVGVISIAFQFCPDHKAAMVLFLDRVYVQDFLLHLLGFLPDLR AAASLTDMALALNRYLCTAVLPLLLFAGTEHHASLIDSLLHTVKGCSLTKAQRDSIEVCL LSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHYERCWKYYCLPGGASEEELHLSRKLFWG IFDALYEQELFKLALPCLSAVAGALPPNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKW SMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERT REGDDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLL VPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGYFLSAASRPLCSGGHASNKEKEMVF CKLGVLVRHRISLFGNDATLHILGQTLDARTVMKTGLESVKFLDNAAEDLEKTMENLKQG QFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYRILTSLYALGTSVERQRSALGECLAAF AGAAFLETHLDKHNIYSYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPRVDP LHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCSFEEKEMEKQKLLYQQARLHDRGA AEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLEYLKEKKDVGFFQSLAGL MQSCSVLDLNAFERQNKAEGKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTT VNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGP CTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLE GNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRD FHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSE HMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKE SKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQIIAYQQKLLNYFARNFYNMRML ALFVAFAINFILLFYKVSVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLV IFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYG EFYGRDRISELLGVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMG FKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDM LTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDA FGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKD ETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYE

Structure information

PDB ID	6jh6 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of RyR2 (F/A/Ca2+ dataset)
Assembly ID	1
Resolution	4.8Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	165
Sequence identity between the two chains	1.0
PubMed citation	31792195

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	F	H
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:6jh6F	BioLiP:6jh6H

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 6jh6-a1-m1-cF_6jh6-a1-m1-cH.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 6jh6-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6jh6/1/1:B/1:D 6jh6/1/1:B/1:H 6jh6/1/1:D/1:F