6jii/1/1:H/1:K

Sequences

>6jii-a1-m1-cH (length=3508) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHSYSGMYLCCLSTSRKLAFDVGLQEDTTGEACW WTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPISSAQGY LIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWG QPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKEKLRKEVDGMGTSEIKY GDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFL FNRFIRGLDALSKKAKTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQN LFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSG SLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDV LCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDH TEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTV SSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVR FLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDT SQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQER NYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAE NAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRA EKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNE HYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVA QVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEV TRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDL VTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKL FPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSR ISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNH RVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMT EETKSITLFPDENKKHGLPGIGLSTSLRPRMQFSSPSFVSINNECYQYSPEFPLDILKAK TIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSG LLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALN ECPCPEEIRDQLLDFHEDLMTHCGIELDLTIRGRLLSLVEKVTYTLQQLISETMVRWAQE SVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSV EEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGPKMVANCCRFLCYFCR ISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKV VRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEAIKIG NAIMTFYAALIDLLGRCAPEMHLIHAAKGEAIRIRSILRSLIPLGDLVGVISIAFQFCPD HKAAMVLFLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLAGTEHHA SLIDSLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHY ERCWKYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQP VDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSE KEKEIYRWPIKESLKTMLAWGWRIERTREGDAAHGYSPRAIDMSNVTLSRDLHAMAEMMA ENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSR GYFLSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMK TGLESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYR ILTSLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSSKQRKRAVVACFRMAPL YNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKC KLEEDFLYMAYADIMAKSCSFEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGP MVAATLKLGIAILNGGNSTVQQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNK AEGLGMKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRV QESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLW DAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVD MLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQS ETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLEL AESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGG EKEKMELFVNFCEDTIFEMQLAAQIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLF YKVSVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEF DGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGS AVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRT ILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMF HMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRD QQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTG QESYVWKMYQERCWEFFPAGDCFRKQYE

>6jii-a1-m1-cK (length=3508) [Search sequence]

QFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHSYSGMYLCCLSTSRKLAFDVGLQEDTTGEACW WTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYLHVDAAFQQTLWSVAPISSAQGY LIGGDVLRLLHGECLTVPSGEHEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWG QPFRLRHVTTGKYLSLMEDKSLLLMDKEKADVKSTAFTFRSSKEKLRKEVDGMGTSEIKY GDSVCFIQHIGTGLWLTYQSSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFL FNRFIRGLDALSKKAKTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQN LFQEEGMINLVLECIDRLHVYSSVAGREAGESWKSILNSLYELLAALIRGNRKNCAQFSG SLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDV LCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGKKWYYELMVDH TEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTV SSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVR FLLGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTRDLLGPTVSAFTPIPVDT SQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQER NYNLQMSLETLKTLLALGCHVGISDEHAYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAE NAHNVWARDRIRQRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEARFRIFRA EKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQGNE HYGRSWQAGDVVGCMVDMTEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVA QVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSSHEHIEV TRIDVTQKSFGSQNSSTDIMFYRLSMPIECTYYYSVRIFPNVWVGWITSDFHQYDTAFDL VTVTLGDEKGKVHESIKRSNYMVCANNNGLEIGCVVGLLTFTANGKDLSTYYQVEPSTKL FPAVFAQATSPNVFQFEAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSR ISERQGWLVQCLEPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNH RVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMT EETKSITLFPDENKKHGLPGIGLSTSLRPRMQFSSPSFVSINNECYQYSPEFPLDILKAK TIQMLTEAVQEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSG LLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALN ECPCPEEIRDQLLDFHEDLMTHCGIELDLTIRGRLLSLVEKVTYTLQQLISETMVRWAQE SVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSV EEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGPKMVANCCRFLCYFCR ISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKV VRYLAGCGLPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPEGLLAAMEEAIKIG NAIMTFYAALIDLLGRCAPEMHLIHAAKGEAIRIRSILRSLIPLGDLVGVISIAFQFCPD HKAAMVLFLDRVYVQDFLLHLLGFLPDLRAAASLTDMALALNRYLCTAVLPLLAGTEHHA SLIDSLLHTVKGCSLTKAQRDSIEVCLLSRPSMMQHLLRRLVFDVPLLNKMPLKLLTNHY ERCWKYYCLPGGASEEELHLSRKLFWGIFDALYEQELFKLALPCLSAVAGALPPNFNPQP VDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSE KEKEIYRWPIKESLKTMLAWGWRIERTREGDAAHGYSPRAIDMSNVTLSRDLHAMAEMMA ENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSR GYFLSAASRPLCSGGHASNKEKEMVFCKLGVLVRHRISLFGNDATLHILGQTLDARTVMK TGLESVKFLDNAAEDLEKTMENLKQGQFTTTVALLPMLSSLFEHIGQHQFLEDVQVSCYR ILTSLYALGTSVERQRSALGECLAAFAGAAFLETHLDKHNIYSSKQRKRAVVACFRMAPL YNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPRVDPLHQLILLFSRTALTEKC KLEEDFLYMAYADIMAKSCSFEEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGP MVAATLKLGIAILNGGNSTVQQKMLEYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNK AEGLGMKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRV QESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLW DAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVD MLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQS ETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLEL AESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGG EKEKMELFVNFCEDTIFEMQLAAQIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLF YKVSVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEF DGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGS AVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRT ILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMF HMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRD QQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTG QESYVWKMYQERCWEFFPAGDCFRKQYE

Structure information

PDB ID	6jii (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of RyR2 (F/A/C/L-Ca2+/apo-CaM-M dataset)
Assembly ID	1
Resolution	4.2Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	109
Sequence identity between the two chains	1.0
PubMed citation	31278385

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	H	K
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:6jiiH	BioLiP:6jiiK

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 6jii-a1-m1-cH_6jii-a1-m1-cK.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 6jii-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6jii/1/1:B/1:E 6jii/1/1:B/1:K 6jii/1/1:E/1:H