6lrk/1/1:A/1:B

Sequences
>6lrk-a1-m1-cA (length=352) [Search sequence]
APGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHV
KISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPLSQFLEGEILSASKMLSKFRK
IIKEEINDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLS
AKVRKQLRLKPFYLVPKHAKGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKD
CLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCV
TYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFD
>6lrk-a1-m1-cB (length=353) [Search sequence]
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKI
SAPNEFDVMFKLEVRIQLEEYSNTRAYYFVKFKRNPLSQFLEGEILSASKMLSKFRKIIK
EEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLS
AKVRKQLRLKPFYLVPKHAKEGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRK
DCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNC
VTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFD
Structure information
PDB ID 6lrk (database links: RCSB PDB PDBe PDBj PDBsum)
Title Human cGAS catalytic domain bound with compound 40
Assembly ID 1
Resolution 2.25Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 35
Sequence identity between the two chains 0.991
PubMed citation 32459092
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession Q8N884 Q8N884
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6lrkA BioLiP:6lrkB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 6lrk-a1-m1-cA_6lrk-a1-m1-cB.pdb.gz
Full biological assembly
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black quality]   [White quality]  
Download: 6lrk-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 5v8o/1/1:B/1:A 6lrc/1/1:B/1:A 6lre/1/1:A/1:B

[Back to Home]