6nq2/1/1:A/1:B

Sequences
>6nq2-a1-m1-cA (length=621) [Search sequence]
AARWDLCIDQAVVFIEDAIQYRSINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAF
IETPSSLTSTADVRYRAAPWEPPCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWL
LGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMAS
VGLLLAIHLCLFTMFGMLLFAGLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYA
IFFIVFTVIGSLFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGAVG
VKPQNLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPE
YQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVF
IVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLSLWDMTRMLNM
LIVFRFLRIIPSMKPMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALS
APCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLV
SSVIWVNLFLALILENFLHKW
>6nq2-a1-m1-cB (length=621) [Search sequence]
AARWDLCIDQAVVFIEDAIQYRSINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAF
IETPSSLTSTADVRYRAAPWEPPCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWL
LGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMAS
VGLLLAIHLCLFTMFGMLLFAGLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYA
IFFIVFTVIGSLFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGAVG
VKPQNLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPE
YQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVF
IVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLSLWDMTRMLNM
LIVFRFLRIIPSMKPMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALS
APCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLV
SSVIWVNLFLALILENFLHKW
Structure information
PDB ID 6nq2 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Cryo-EM structure of human TPC2 channel in the ligand-bound closed state
Assembly ID 1
Resolution 3.4Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 215
Sequence identity between the two chains 1.0
PubMed citation 30860481
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession Q8NHX9 Q8NHX9
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6nq2A BioLiP:6nq2B
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6nq2-a1-m1-cA_6nq2-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 6nq2-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 6nq0/1/1:A/1:B 6nq1/1/1:A/1:B

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