6nxz/1/2:A/4:A

Sequences
>6nxz-a1-m2-cA (length=56) [Search sequence]
ATFGMGDRVRKKSGAAWQGQIVGWYCTNLTPEGYAVESEAHPGSVQIYPVAALERI
>6nxz-a1-m4-cA (length=56) [Search sequence]
ATFGMGDRVRKKSGAAWQGQIVGWYCTNLTPEGYAVESEAHPGSVQIYPVAALERI
Structure information
PDB ID 6nxz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Assembly ID 1
Resolution 1.75Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 46
Sequence identity between the two chains 1.0
PubMed citation 31460098
Chain information
Chain 1 Chain 2
Model ID 2 4
Chain ID A A
UniProt accession P00383 P00383
Species 562 (Escherichia coli) 562 (Escherichia coli)
Function annotation BioLiP:6nxzA BioLiP:6nxzA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 6nxz-a1-m2-cA_6nxz-a1-m4-cA.pdb.gz
Full biological assembly
Download: 6nxz-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 1vie/1/1:A/3:A 1vie/1/2:A/4:A 1vif/1/1:A/3:A 1vif/1/2:A/4:A 2gqv/1/1:A/3:A 2gqv/1/2:A/4:A 2p4t/1/1:A/2:A 2p4t/1/3:A/4:A 2rh2/1/1:A/2:A 2rh2/1/3:A/4:A 2rh2/2/1:A/2:A 2rk1/1/1:A/3:A 2rk1/1/2:A/4:A 2rk2/1/1:A/3:A 2rk2/1/2:A/4:A 3sfm/1/1:A/3:A 3sfm/1/2:A/4:A 6nxz/1/1:A/3:A 6ny0/1/1:A/3:A 6ny0/1/2:A/4:A
Other dimers with similar sequences but different poses
  • 6nxz/1/1:A/4:A 1vie/1/1:A/2:A 1vie/1/3:A/4:A 1vif/1/1:A/2:A 1vif/1/3:A/4:A 2gqv/1/1:A/4:A 2gqv/1/2:A/3:A 2p4t/1/1:A/4:A 2p4t/1/2:A/3:A 2rh2/1/1:A/3:A 2rh2/1/2:A/4:A 2rk1/1/1:A/4:A 2rk1/1/2:A/3:A 2rk2/1/1:A/4:A 2rk2/1/2:A/3:A 3sfm/1/1:A/4:A 3sfm/1/2:A/3:A 6nxz/1/2:A/3:A 6ny0/1/1:A/4:A 6ny0/1/2:A/3:A
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