6orr/5/1:A/2:C

Sequences

>6orr-a5-m1-cA (length=271) [Search sequence]

HHSSGLVPRGSMESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIF
CLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKAAPAAFDWSP
VVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAA
CPDLPTYCRALRNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAG
YTIEWFEVISQSYSSTMANNEGLFSLVARKL

>6orr-a5-m2-cC (length=273) [Search sequence]

Structure information

PDB ID	6orr (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Co-crystal structure of human NicotinamideN-Methyltransferase (NNMT) in complex with High-Affinity Alkynyl Bisubstrate Inhibitor NS1
Assembly ID	5
Resolution	2.25Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	17
Sequence identity between the two chains	1.0
PubMed citation	31589440

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	C
UniProt accession	P40261	P40261
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:6orrA	BioLiP:6orrC

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

6orr-a5-m1-cA_6orr-a5-m2-cC.pdb.gz

Full biological assembly

Download:

6orr-assembly5.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

6orr/5/2:B/2:C 6chh/1/1:C/1:A 6chh/1/1:D/2:B 6orr/5/1:D/1:A

6orr/5/1:D/2:C 6chh/1/1:C/2:B 6chh/1/1:D/1:A 6orr/5/2:B/1:A