6uoz/1/1:B/1:A

Sequences
>6uoz-a1-m1-cB (length=302) [Search sequence]
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI
DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK
WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS
DC
>6uoz-a1-m1-cA (length=304) [Search sequence]
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI
DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG
GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW
KSDC
Structure information
PDB ID 6uoz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the WDR5-MYC interaction
Assembly ID 1
Resolution 1.532Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 28
Sequence identity between the two chains 1.0
PubMed citation 32223236
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession P61964 P61964
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6uozB BioLiP:6uozA
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6uoz-a1-m1-cB_6uoz-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 6uoz-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 8f93/2/1:A/1:B 8f93/1/1:A/1:B
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