6vp8/1/1:C/1:A

Sequences
>6vp8-a1-m1-cC (length=319) [Search sequence]
LTRRILLPKNVIVECMVATHHASIWLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLA
LVHLPVEKESWIVSGTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNFLLVGTADGKLA
IFEDKTVKLKGAAPLKILNIGNVSTPLMCLSESNVMWGGCGTKIFSFSNDFTIQKLIETR
TSQLFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEKLCGLIDCVHFLREVMMS
YSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFCNSVRVMMTAQLGSLKNV
MLVLGYNREIQSCLTVWDI
>6vp8-a1-m1-cA (length=1083) [Search sequence]
VPYNRMKLMIVGNGSGKTTLLQQLMGIDVKDWPILVLNVWDFAGREEFYSTHPRALYLAV
YDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACMSKITKELLNKRG
FPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSER
KNVPIEFPVIDRKRLLQLVRENQLQLDENELPHAVHFLNESGVLLHFQALQLSDLYFVEP
KWLCKIMAQILTVGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGEEYLLVP
SSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLLRPNRMYWRQ
GIYLNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLL
LLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLILADLPR
NIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQELVVLCH
LHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLH
SAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGPGFRAPEVARGNVIYNQQADVYSFGLL
LYDILTTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKENPQER
PTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHHASIWLGCGHTDRGQLSFLDLNT
EGYTSEEVADSRILCLALVHLPVEKESWIVSGTQSGTLLVINTEDGKKRHTLEKMTDSVT
CLYCNFLLVGTADGKLAIFEDKTVKLKGAAPLKILNIGNVSTPLMCLSESNVMWGGCGTK
IFSFSNDFTIQKLIETRTSQLFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEK
LCGLIDCVHFLREVMMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFC
NSVRVMMTAQLGSLKNVMLVLGYNREIQSCLTVWDINLPHEVQNLEKHIEVRKELAEKMR
RTS
Structure information
PDB ID 6vp8 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Assembly ID 1
Resolution 3.5Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 53
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID C A
UniProt accession Q5S007 Q5S007
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6vp8-a1-m1-cC_6vp8-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 6vp8-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 6vp6/1/1:B/1:A 6vp6/1/1:C/1:A 6vp8/1/1:B/1:A

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