6wkz/1/1:A/2:B

Sequences
>6wkz-a1-m1-cA (length=294) [Search sequence]
STQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQRPLT
SCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFLREN
GINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVY
YWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIIL
GGGVVKHHGADYAVYINTAQEFDGSQPVKVYADASLVFPLLVAETFAQKMDAFM
>6wkz-a1-m2-cB (length=296) [Search sequence]
STQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQTQSRRPLT
SCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFELRE
NGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESV
YYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMII
LGGGVVKHHGADYAVYINTAQEFDGSDQPVKVYADASLVFPLLVAETFAQKMDAFM
Structure information
PDB ID 6wkz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Cocomplex structure of Deoxyhypusine synthase with inhibitor 6-[(1R)-2-AMINO-1-PHENYLETHYL]-3-(PYRIDIN-3-YL)-4H,5H,6H,7H-THIENO[2,3-C]PYRIDIN-7-ONE
Assembly ID 1
Resolution 2.23Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 193
Sequence identity between the two chains 0.986
PubMed citation 34345355
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A B
UniProt accession P49366 P49366
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6wkzA BioLiP:6wkzB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6wkz-a1-m1-cA_6wkz-a1-m2-cB.pdb.gz
Full biological assembly
Download: 6wkz-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 6wkz/1/2:A/2:B 6wkz/1/1:A/1:B
  • 6wkz/1/1:A/2:A 6wkz/1/1:B/2:B 6wl6/1/1:A/2:A 6wl6/1/1:B/2:B
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