6x35/1/1:H/1:K

Sequences

>6x35-a1-m1-cH (length=3801) [Search sequence]

QFLRTDDEVVLQCNATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATG EACWWTTHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMN PICSGCEEGYVTGGHVLRLFHGHMDECLTISPADQRRLVYYEGGSVCTHARSLWRLEPLR ISWSGSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLKRD VEGMGPPEIKYGESLCFVQHVASGLWLTYAALKKKAILHQEGHMDDALSLTRCQQEESQA ARMIYSTAGLYNHFIKGLDSFSGKPRPAGTALPLEGVILSLQDLIGYFEPPSEELQHEEK QSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYE ILASLIRGNRANCALFSNNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIK SIISLLDKHGRNHKVLDVLCSLCVCNGVAVCSNQDLITENLLPGRELLLQTNLINYVTSI RPNIFVGRAEGTTQYSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGG NGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPV QGVFEAFNLNGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLE PIKEYRREGPRGPHLVGPSRCLSHTDFVPCPLPPHLERIREKLAENIHELWALTRIEQGW TYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLR KTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQ DIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGRVRIFRAEKSYAVQSGRWYFE FEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGC MIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLGQDVSSL RFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEAVPLEHPHYEVSRVDGTVDTPPCLR LTHRSLVEMLFLRLSLPVQFHQLNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFD LTKVRAVTVTMGDNIHSSLKCSNCYMVWGGDFVSHTDLVIGCLVDLATGLMTFTANGKES NTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLE MQMLMPVSWSRMPNHFLRVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSER LDLQQFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLI SIHLESACRSRRSMLSEYIVPLTPETRAITLFPPRHGLPGVGVTTSLRPPHHFSAPCFVA ALPEAPARLSPSIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLL VMGIFGDEDVKQILKMIEPEVEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAF AERYVDKLQANQRDRYGILMKAFTMTAAETARRTREFRSPPQEQINMLLHFKPLPDEIRQ DLLEFHQDLLTHCGIQLQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGEL LRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQH PNLMRALGMHETVMEVMVNVLGRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENS GSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGG ERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRLLATIEEAIGHAIMSFYAA LIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPLMSASFVPDHK ASMVLFLDRVYGIEFLLHVLDVGFEMALALNRYLCLAVLPLITKCAPLFAMVDSMLHTVY RLSRGRSLTKAQRDVIEECLMALCRYIRPSMLQHLLRRLVFXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAF DKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKARE GEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLT AKEKARDREKAQELLKFLQMNGYAVTRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNPSAEELFRMVGEIFIYWSKSH NFKREEQNFVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSF EDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIM AKSCHLEESFEEKEMEKQRLLYQQARLHNRGAAEMVLQMISACKGETGAMVSSTLKLGIS ILNGGNADVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG TVIGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQ ESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWD AVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDM LVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKXXXXXXEEFANR FQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIE RIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQXXXXX XXXXXXXXXXXXEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPVYYFL EESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQP EDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAEGLLTWLMSIDVKY QIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGK QLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGG GIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDME TKCFICGIGSDYFDTTPHRFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQ ERCWDFFPAGDCFRKQYEDQL

>6x35-a1-m1-cK (length=3801) [Search sequence]

QFLRTDDEVVLQCNATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQ SLSVRALQEMLANGHRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATG EACWWTTHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMN PICSGCEEGYVTGGHVLRLFHGHMDECLTISPADQRRLVYYEGGSVCTHARSLWRLEPLR ISWSGSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLKRD VEGMGPPEIKYGESLCFVQHVASGLWLTYAALKKKAILHQEGHMDDALSLTRCQQEESQA ARMIYSTAGLYNHFIKGLDSFSGKPRPAGTALPLEGVILSLQDLIGYFEPPSEELQHEEK QSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYE ILASLIRGNRANCALFSNNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIK SIISLLDKHGRNHKVLDVLCSLCVCNGVAVCSNQDLITENLLPGRELLLQTNLINYVTSI RPNIFVGRAEGTTQYSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGG NGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPV QGVFEAFNLNGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLE PIKEYRREGPRGPHLVGPSRCLSHTDFVPCPLPPHLERIREKLAENIHELWALTRIEQGW TYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLR KTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQ DIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGRVRIFRAEKSYAVQSGRWYFE FEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGC MIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLGQDVSSL RFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEAVPLEHPHYEVSRVDGTVDTPPCLR LTHRSLVEMLFLRLSLPVQFHQLNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFD LTKVRAVTVTMGDNIHSSLKCSNCYMVWGGDFVSHTDLVIGCLVDLATGLMTFTANGKES NTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLE MQMLMPVSWSRMPNHFLRVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSER LDLQQFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLI SIHLESACRSRRSMLSEYIVPLTPETRAITLFPPRHGLPGVGVTTSLRPPHHFSAPCFVA ALPEAPARLSPSIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLL VMGIFGDEDVKQILKMIEPEVEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAF AERYVDKLQANQRDRYGILMKAFTMTAAETARRTREFRSPPQEQINMLLHFKPLPDEIRQ DLLEFHQDLLTHCGIQLQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGEL LRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQH PNLMRALGMHETVMEVMVNVLGRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENS GSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGG ERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRLLATIEEAIGHAIMSFYAA LIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPLMSASFVPDHK ASMVLFLDRVYGIEFLLHVLDVGFEMALALNRYLCLAVLPLITKCAPLFAMVDSMLHTVY RLSRGRSLTKAQRDVIEECLMALCRYIRPSMLQHLLRRLVFXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAF DKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKARE GEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLT AKEKARDREKAQELLKFLQMNGYAVTRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNPSAEELFRMVGEIFIYWSKSH NFKREEQNFVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSF EDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIM AKSCHLEESFEEKEMEKQRLLYQQARLHNRGAAEMVLQMISACKGETGAMVSSTLKLGIS ILNGGNADVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG TVIGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQ ESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWD AVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDM LVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKXXXXXXEEFANR FQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIE RIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQXXXXX XXXXXXXXXXXXEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPVYYFL EESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQP EDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAEGLLTWLMSIDVKY QIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGK QLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGG GIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDME TKCFICGIGSDYFDTTPHRFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQ ERCWDFFPAGDCFRKQYEDQL

Structure information

PDB ID	6x35 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Pig R615C RyR1 in complex with CaM, EGTA (class 1, open)
Assembly ID	1
Resolution	4.2Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	150
Sequence identity between the two chains	1.0
PubMed citation	33547325

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	H	K
UniProt accession
Species	9823 (Sus scrofa)	9823 (Sus scrofa)
Function annotation	BioLiP:6x35H	BioLiP:6x35K

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 6x35-a1-m1-cH_6x35-a1-m1-cK.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 6x35-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6x35/1/1:B/1:E 6x35/1/1:B/1:K 6x35/1/1:E/1:H