7d5l/1/1:A/1:E

Sequences
>7d5l-a1-m1-cA (length=193) [Search sequence]
KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSI
NGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVT
RHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVD
FIPVESLETTMRS
>7d5l-a1-m1-cE (length=193) [Search sequence]
KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSI
NGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVT
RHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVD
FIPVESLETTMRS
Structure information
PDB ID 7d5l (database links: RCSB PDB PDBe PDBj PDBsum)
Title Discovery of BMS-986144, a Third Generation, Pan Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
Assembly ID 1
Resolution 2.15Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 17
Sequence identity between the two chains 1.0
PubMed citation 33226226
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A E
UniProt accession A0A0B4WYC6 A0A0B4WYC6
Species 11103 () 11103 ()
Function annotation BioLiP:7d5lA BioLiP:7d5lE
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 7d5l-a1-m1-cA_7d5l-a1-m1-cE.pdb.gz
Full biological assembly
Download: 7d5l-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 2o8m/1/1:B/1:A 1a1r/3/1:A/1:B 1n1l/3/1:B/1:A 1rgq/1/1:A/1:B 1rtl/1/1:B/1:A 2a4g/1/1:C/1:A 2a4q/1/1:C/1:A 2a4r/1/1:C/1:A 2f9u/1/1:C/1:A 2f9v/1/1:C/1:A 2fm2/1/1:C/1:A 2gvf/3/1:C/1:A 2obo/1/1:C/1:A 2obq/1/1:C/1:A 2oc0/1/1:C/1:A 2oc1/1/1:C/1:A 2oc7/1/1:C/1:A 2oc8/1/1:C/1:A 2oin/3/1:A/1:B 2xcf/1/1:B/1:A 2xcn/1/1:B/1:A 2xni/1/1:B/1:A 3eyd/3/1:C/1:A 3kf2/1/1:A/1:B 3kn2/3/1:C/1:A 3lon/1/1:C/1:A 3lox/1/1:C/1:A
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