7dv4/2/1:C/1:E

Sequences

>7dv4-a2-m1-cC (length=113) [Search sequence]

KAMHVAQPAVVLASSRGIASFVCEYATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDD SICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVID

>7dv4-a2-m1-cE (length=116) [Search sequence]

MHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTF LDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVID

Structure information

PDB ID	7dv4 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4
Assembly ID	2
Resolution	2.38Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	31
Sequence identity between the two chains	0.982

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	C	E
UniProt accession	P16410	P16410
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 7dv4-a2-m1-cC_7dv4-a2-m1-cE.pdb.gz

Full biological assembly Download: 7dv4-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

1i85/1/1:D/1:C 3bx7/1/1:C/2:C 3osk/1/1:A/1:B 6rpj/2/1:C/1:E 6rpj/1/1:G/2:A