7eg4/1/1:B/1:D

Sequences
>7eg4-a1-m1-cB (length=567) [Search sequence]
NISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKA
EIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITT
LSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALA
GVFFDRTELDRKEKLTFTESTHVEIKNFSTERLLQRIKEILPQYVSAFANTDGGYLFIGL
NEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGY
VCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSAYEEVISQINT
SLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMSSVRKGS
LIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQKL
AKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRL
KSLRDQFSFAENLYQIIGIDCFQKNDK
>7eg4-a1-m1-cD (length=567) [Search sequence]
NISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKA
EIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITT
LSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALA
GVFFDRTELDRKEKLTFTESTHVEIKNFSTERLLQRIKEILPQYVSAFANTDGGYLFIGL
NEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGY
VCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSAYEEVISQINT
SLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMSSVRKGS
LIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQKL
AKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRL
KSLRDQFSFAENLYQIIGIDCFQKNDK
Structure information
PDB ID 7eg4 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex
Assembly ID 1
Resolution 3.2Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 196
Sequence identity between the two chains 1.0
PubMed citation 34707099
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B D
UniProt accession Q8IYM2 Q8IYM2
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:7eg4B BioLiP:7eg4D
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 7eg4-a1-m1-cB_7eg4-a1-m1-cD.pdb.gz
Full biological assembly
Download: 7eg4-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 7eg0/1/1:B/1:D 7eg1/1/1:B/1:D 7lrd/1/1:A/1:C 7lre/1/1:A/1:B

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